The European Agency for the Evaluation of Medicinal Products Veterinary Medicines Evaluation Unit

1. Toltrazuril, a triazinetrione derivative, is intended for use in chickens and turkeys for the prevention and treatment of coccidiosis. Administration is via drinking water at 25 mg/l for continuous administration over 48 hours or at 75 mg/l given for 8 hours per day, on 2 consecutive days. Both treatments correspond to a dose of approximately 7 mg toltrazuril/kg bw/day. For curative treatment, one medication that can be repeated after 5 days is recommended and for preventive treatment of chickens, three medications on days 9 to 10, 16 to 17 and 23 to 24 of life.